全文获取类型
收费全文 | 1556篇 |
免费 | 65篇 |
国内免费 | 99篇 |
专业分类
系统科学 | 84篇 |
丛书文集 | 34篇 |
教育与普及 | 17篇 |
理论与方法论 | 9篇 |
现状及发展 | 120篇 |
综合类 | 1455篇 |
自然研究 | 1篇 |
出版年
2024年 | 3篇 |
2023年 | 23篇 |
2022年 | 46篇 |
2021年 | 21篇 |
2020年 | 35篇 |
2019年 | 20篇 |
2018年 | 23篇 |
2017年 | 29篇 |
2016年 | 29篇 |
2015年 | 43篇 |
2014年 | 76篇 |
2013年 | 45篇 |
2012年 | 66篇 |
2011年 | 96篇 |
2010年 | 70篇 |
2009年 | 85篇 |
2008年 | 82篇 |
2007年 | 116篇 |
2006年 | 107篇 |
2005年 | 89篇 |
2004年 | 92篇 |
2003年 | 89篇 |
2002年 | 72篇 |
2001年 | 53篇 |
2000年 | 44篇 |
1999年 | 44篇 |
1998年 | 28篇 |
1997年 | 35篇 |
1996年 | 31篇 |
1995年 | 19篇 |
1994年 | 25篇 |
1993年 | 10篇 |
1992年 | 14篇 |
1991年 | 17篇 |
1990年 | 8篇 |
1989年 | 6篇 |
1988年 | 8篇 |
1987年 | 5篇 |
1986年 | 5篇 |
1985年 | 7篇 |
1984年 | 2篇 |
1981年 | 1篇 |
1955年 | 1篇 |
排序方式: 共有1720条查询结果,搜索用时 468 毫秒
1.
“百病生于气”见于《素问·举痛论》,几千年来始终是中医临床认识疾病、防治疾病的重要理论依据之一。对气的含义及气机失调致病的机制进行了梳理,得出了“百病生于气”的基本含义可以概括为气机失调是疾病发生的基本病机的结论,情志因素、精神心理是导致疾病发生的重要内因。分析认为“百病生于气”的理论对于针灸临床有重要指导意义,针灸诊疗过程中应注重“调气”“调神”,这是针灸取得佳效的根本保障。 相似文献
2.
为了探究环境规制政策对于环境污染及公共健康的影响,本文基于我国1978至2013年颁布的976条环境规制政策,利用从政策属性力度、政策内容力度两个维度对我国环境规制政策进行量化的数据,构建了针对环境规制政策效果的计量模型,通过将中介效应检验方法引入环境健康经济学分析,检验了环境污染对环境规制政策与公共健康的中介效应.研究结果表明:环境规制政策对公共健康具有促进作用;我国总体的环境规制政策对于防治环境污染产生了一定程度的积极效果;环境规制政策通过对环境污染显著的部分中介效应进而对公共健康产生了促进作用.本研究基于总体环境规制政策文献量化角度考察的"政策-环境-健康"三维动态关系结果,阐明了环境规制政策、环境污染以及公共健康三者的影响传输路径,对于有效评估环境规制政策效果,保障环境质量以及公共健康的可持续提升具有理论借鉴价值. 相似文献
3.
In this paper, a series of examples from China, including those using ecological regulation strategies successfully to keep crop pests under control and those making more damages of crop pests caused by wrong cropping systems, crop distributions or extensive cultivation, were given and analyzed. From these, two pieces of experience were enlightened as follows: the first, the refoms of cropping systems and crop distributions must be beneficial to pest control or at least not increase the damage of crop pests; the second, we should further clarify the relationship between population dynamics of pests and cropping system/crop distribution, the basis for correctly laying down the ecological regulation systems. 相似文献
4.
Crnković-Mertens I Wagener N Semzow J Gröne EF Haferkamp A Hohenfellner M Butz K Hoppe-Seyler F 《Cellular and molecular life sciences : CMLS》2007,64(9):1137-1144
Cancer cells are typically characterized by apoptosis deficiency. In order to investigate a possible role for the anti-apoptotic
livin gene in renal cell cancer (RCC), we analyzed its expression in tumor tissue samples and in RCC-derived cell lines. In addition,
we studied the contribution of livin to the apoptotic resistance of RCC cells by RNA interference (RNAi). Livin gene expression was detected in a significant portion of RCC tumor tissue specimens (13/14, 92.9%) and tumor-derived cell
lines (12/15, 80.0%). Moreover, targeted inhibition of livin by RNAi markedly sensitized RCC cells towards proapoptotic stimuli, such as UV irradiation or the chemotherapeutic drugs
etoposide, 5-fluorouracil, and vinblastine. These effects were specific for livin expressing tumor cells. We conclude that livin can contribute significantly to the apoptosis resistance of RCC cells. Targeted inhibition of livin could represent a novel therapeutic strategy to increase the sensitivity of renal cancers towards pro-apoptotic agents.
Received 30 November 2006; received after revision 22 February 2007; accepted 20 March 2007 相似文献
5.
离心式风机导流器调节的经济性分析 总被引:3,自引:0,他引:3
全面分析和比较了G4-73型离心风机在较大负荷变化范围内分别采用轴向导流器调节和轴向导流器加双速电动机调节的运行经济性,对各种风机的节能具有重要的指导意义。 相似文献
6.
提出了利用上位机参与实时控制,综合分析在线参数、离线参数和间接参数,辅助发酵过程工艺研究和优化控制,并给出了上位机软件包的部分源程序及框图。该软件包对发酵工艺人员进一步了解菌种的遗传特性、细胞代谢调节和反应器工程特性方面有较大帮助。 相似文献
7.
广西电网需电量迅猛增加,峰谷差越来越大,迫切需要大量调峰容量。由于广西电网电源结构不合理,水电站调节性能差,枯水期出力小,火电机组最小技术出力高,电网调峰能力不足,汛期基荷容量过剩,造成低谷时大量弃水。建设抽水蓄能电站可以发挥其调峰、填谷双重作用,是当前解决电网调峰行之有效的最佳措施,应加紧实施。 相似文献
8.
陆化平 《科技情报开发与经济》2005,15(18):293-295
概述了缓冲区养护中存在的问题,分析了无缝线路缓冲区病害的成因,提出了治理病害的针对性措施. 相似文献
9.
SHENG Qi-zheng De Moor Bart 《上海大学学报(自然科学版)》2004,10(Z1):106-108
As a newborn interdisciplinary field, bioinformatics is receiving increasing attention from biologists, computer scientists, statisticians, mathematicians and engineers. This paper briefly introduces the birth, importance, and extensive applications of bioinformatics in the different fields of biological research. A major challenge in bioinformatics - the unraveling of gene regulation - is discussed in detail. 相似文献
10.
Dhar-Chowdhury P Malester B Rajacic P Coetzee WA 《Cellular and molecular life sciences : CMLS》2007,64(23):3069-3083
Glycolysis is an evolutionary conserved metabolic pathway that provides small amounts of energy in the form of ATP when compared
to other pathways such as oxidative phosphorylation or fatty acid oxidation. The ATP levels inside metabolically active cells
are not constant and the local ATP level will depend on the site of production as well as the respective rates of ATP production,
diffusion and consumption. Membrane ion transporters (pumps, exchangers and channels) are located at sites distal to the major
sources of ATP formation (the mitochondria). We review evidence that the glycolytic complex is associated with membranes;
both at the plasmalemma and with membranes of the endo/sarcoplasmic reticular network. We examine the evidence for the concept
that many of the ion transporters are regulated preferentially by the glycolytic process. These include the Na+/K+-ATPase, the H+-ATPase, various types of Ca2+-ATPases, the Na+/H+ exchanger, the ATP-sensitive K+ channel, cation channels, Na+ channels, Ca2+ channels and other channels involved in intracellular Ca2+ homeostasis. Regulation of these pumps, exchangers and ion channels by the glycolytic process has important consequences
in a variety of physiological and pathophysiological processes, and a better understanding of this mode of regulation may
have important consequences for developing future strategies in combating disease and developing novel therapeutic approaches.
Received 20 July 2007; received after revision 30 July 2007; accepted 17 August 2007 相似文献